Best DNA Tests in 2026: Our Top Picks After Testing 10+ Kits
We compared AncestryDNA, 23andMe, MyHeritage, FamilyTreeDNA, and Sequencing.com to find the best DNA test for ancestry, health, and finding relatives in 2026.
Our top pick for ancestry
After testing kits from every major brand, AncestryDNA remains the best general ancestry test for one reason: database size. The matching tool only works as well as the pool of people you can match to, and Ancestry’s pool is roughly twice the size of its nearest competitor.
AncestryDNA
Ancestry
- Price
- $39 (MSRP $99)
- Turnaround
- 4-6 wks
- Database
- approx 25-30 million
Largest consumer DNA database, deep US historical records integration, ThruLines and SideView tools.
Check current pricePricing checked 2026-05-26. DNA test prices change often — confirm on the merchant page.
Best for combined ancestry plus health
If you want both ancestry and basic health reporting in one kit and you’ve read the privacy caveats, 23andMe is still the most established option in this category.
Best whole-genome sequencing
Nebula Genomics shut down in early 2025. The active replacement is Sequencing.com, which offers whole-genome kits plus an app marketplace for third-party analysis.
The full comparison
A side-by-side comparison of all five tests we tested:
| Test | Best for | Database | Turnaround | Price |
|---|---|---|---|---|
| AncestryDNA | Ancestry, matching | ~25-30M | 4-6 wks | $99 |
| 23andMe | Ancestry + health | ~14M | 3-5 wks | $99 |
| MyHeritage | European ancestry | ~5-8M | 3-4 wks | $89 |
| FamilyTreeDNA | Y-DNA, deep lineage | ~2-3M | 4-6 wks | $79 |
| Sequencing.com | Whole-genome data | n/a | varies | varies |
For the broader framework on how to choose a test, see the guide to DNA testing pillar.
Sources
- Direct-to-Consumer Genetic Testing: Considerations for the Primary Care Physician — ACMG Primary
- Find a Genetic Counselor — National Society of Genetic Counselors Primary